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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human brain
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CLDND1
Abbre CLDND1
Synonyms C3orf4,  Chromosome 3 open reading frame 4,  Claudin domain containing 1,  Claudin domain containing 1 protein,  GENX 3745,  MGC111162,  MGC3316,  MGC9861,  Membrane protein GENX3745,  OTTHUMP00000,  OTTHUMP00000217407,  OTTHUMP00000217408,  OTTHUMP00000217423,  OTTHUMP00000217424
Swissprot
Cellular Localization Membrane, Multi pass membrane protein.
Concentration 0.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cell Biology,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
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Unconjugated

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