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CLK2 Polyclonal Antibody (E-AB-53303)

All Size Price Qty
200μL $ 399.00
120μL $ 240.00
60μL $ 143.00
20μL $ 73.00
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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human ovarian cancer
Dilution IHC 1:30-1:150
Clonality Polyclonal
Immunogen Synthetic peptide of human CLK2
Abbre CLK2
Synonyms CDC like kinase 2,  CDC-like kinase 2,  CLK 2,  CLK kinase,  CLK2,  Clk2 Scamp3,  Dual specificity protein kinase CLK2,  Tu52,  hCLK 2,  hCLK2
Swissprot
Cellular Localization Nucleus.
Concentration 0.5 mg/mL
Buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method Antigen affinity purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates.Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing.Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein.Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation.There is a pseudogene for this gene on chromosome 7.Alternative splicing results in multiple transcript variants.
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Unconjugated

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