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For research use only.

Verified Samples Verified Samples in IHC: Human esophagus cancer, Human gastric cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CLPS
Abbre CLPS
Synonyms COL,  Colipase,  Colipase pancreatic,  Pancreatic colipase preproprotein,  clpS
Swissprot
Cellular Localization Extracellular region or secreted, extracellular exosome, extracellular region.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis.It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site.The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts.This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements.Three transcript variants encoding different isoforms have been found for this gene.
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Unconjugated

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