CNOT7 Polyclonal Antibody (E-AB-53112)

For research use only.
Verified Samples |
Verified Samples in IHC: Human lung cancer |
Dilution | IHC 1:50-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Fusion protein of human CNOT7 |
Abbre | CNOT7 |
Synonyms | BTG1 binding factor 1, BTG1-binding factor 1, CAF 1, CAF-1, CAF1, CCR4 NOT transcription complex subunit 7, CCR4 associated factor 1, CCR4-NOT transcription complex subunit , CCR4-associated factor 1, Carbon catabolite repressor protein (CCR4) associative factor 1 |
Swissprot | |
Cellular Localization | Nucleus. |
Concentration | 0.96 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.CNOT7 (CCR4-NOT Transcription Complex Subunit 7) is a Protein Coding gene. Among its related pathways are Deadenylation-dependent mRNA decay and Gene Expression. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is CNOT8. |
Other Clones
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Other Formats
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Unconjugated
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