COX17 Polyclonal Antibody (E-AB-19376)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human brain |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human COX17 |
| Abbre | COX17 |
| Synonyms | COX 17, COX17, COX17 cytochrome c oxidase assembly homolog, COX17 cytochrome c oxidase assembly homolog (S. cerevisiae), COX17 homolog cytochrome c oxidase assembly protein, Cytochrome c oxidase copper , cytochrome c oxidase assembly protein cox17 homolog |
| Swissprot | |
| Cellular Localization | Mitochondrion intermembrane space. |
| Concentration | 1.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen.This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes.The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex.This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme.This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins.This gene is no longer considered to be a candidate gene for COX deficiency.A pseudogene COX17P has been found on chromosome 13. |
Other Clones
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Other Formats
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Unconjugated
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