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For research use only.

Verified Samples Verified Samples in IHC: Human breast cancer, Human cervical cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CRABP2
Synonyms CRABP II,  CRABP-II,  CRABPII,  Cellular retinoic acid binding protein 2,  Cellular retinoic acid binding protein II,  Cellular retinoic acid-binding protein 2,  Cellular retinoic acid-binding protein II,  Crabp2,  RABP2,  RBP6,  Rretinoic acid-binding protein,  cellular,  type
Swissprot
Cellular Localization Cytoplasm. Nucleus. Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Other Clones

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Unconjugated

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