CTNNA1 Polyclonal Antibody (E-AB-10207)
For research use only.
| Verified Samples |
Verified Samples in WB: A431 Verified Samples in IHC: Human gastric cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CTNNA1 |
| Abbre | CTNNA1 |
| Synonyms | 102kDa, Alpha E-catenin, CAP 102, CAP102, Cadherin associated protein, Cadherin associated protein 102kDa, Cadherin-associated protein, Catenin (cadherin associated protein), Catenin (cadherin associated protein) alpha 1 102kDa, Catenin alp, Catenin alpha 1, alpha 1 |
| Swissprot | |
| Calculated MW | 100 kDa |
| Cellular Localization | Cell membrane and Cytoplasm>cytoskeleton. Cell junction>adherens junction. Cell membrane. Cell junction. Found at cell-cell boundaries and probably at cell-matrix boundaries. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Catenin alpha-1 is a protein that in humans is encoded by the CTNNA1 gene.Associates with the cytoplasmic domain of a variety of cadherins.The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.Can associate with both E- and N-cadherins.Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions.In contrast, cortical actin was found to be mucHuman, Mouseore dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. |
Other Clones
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Other Formats
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Unconjugated
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