For research use only.
Verified Samples |
Verified Samples in IHC: Human breast cancer, Human thyroid cancer |
Dilution | IHC 1:50-1:100 |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human CXCL1 |
Abbre | CXCL1 |
Synonyms | C-X-C motif chemokine 1, CINC-1, CXCL1, Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, Cytokine-induced neutrophil chemoattractant 1, Fibroblast secretory protein, Fsp, GRO protein, Gro, Gro 1, Gro A, alpha), chemokine (C-X-C motif) ligand 1 |
Swissprot | |
Cellular Localization | Secreted. |
Concentration | 1.02 mg/mL |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Immunology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | CXCL1 (C-X-C Motif Chemokine Ligand 1) is a Protein Coding gene. Diseases associated with CXCL1 include Melanoma and Bacterial Meningitis. Among its related pathways are Peptide ligand-binding receptors and Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions. GO annotations related to this gene include receptor binding and chemokine activity. An important paralog of this gene is CXCL2.This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. |
Other Clones
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Unconjugated
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