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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human gastric cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CYP11A1
Abbre CYP11A1
Synonyms CP11A,  CYP11A,  CYP11A1,  CYPXI,  Cholesterol 20 22 desmolase,  Cholesterol desmolase,  Cholesterol monooxygenase (side chain cleaving),  Cholesterol side chain cleavage enzyme,  Cholesterol side chain cleavage enzyme mitochondrial,  Cholesterol side-chain cleavage enzyme
Swissprot
Cellular Localization Mitochondrion membrane.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
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Unconjugated

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