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For research use only.

Verified Samples Verified Samples in IHC: Human gastric cancer, Human thyroid cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human CYP39A1
Abbre CYP39A1
Synonyms 24 hydroxycholesterol 7 alpha hydroxylase,  24-hydroxycholesterol 7-alpha-hydroxylase,  CP39A,  Cyp39a1,  Cyt,  Cytochrome P450 39A1,  cytochrome P450 family 39,  cytochrome P450 subfamily XXXIX (oxysterol 7 alpha hydroxylase) polypeptide 1,  subfamily A polypeptide 1
Swissprot
Cellular Localization Endoplasmic reticulum membrane. Microsome membrane.
Concentration 0.8 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Alternate splicing results in multiple transcript variants.
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Unconjugated

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