DACH2 Polyclonal Antibody (E-AB-11136)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human liver cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human DACH2 |
| Abbre | DACH2 |
| Synonyms | DACH 2, DACH2, Dach2, Dachshund 2, Dachshund homolog 2, Dachshund homolog 2 (Drosophila), Dachshund2, FLJ31391 , HGNC:16814, MGC138545 |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly.The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions.This gene is located on the X chromosome and is subject to inactivation by DNA methylation.The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure.Multiple transcript variants encoding different isoforms have been found for this gene. |
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