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For research use only.

Verified Samples Verified Samples in WB: Hela
Verified Samples in IHC: Human cervical cancer, Human colon cancer
Dilution WB 1:1000-1:5000,  IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human DCP1A
Abbre DCP1A
Synonyms DCP1 decapping enzyme homolog A,  DCP1A,  Dcp1a,  Decapping enzyme hDcp1a,  Decapping mRNA 1A,  HSA275986,  Nbla00360,  Putative protein product of Nbla00360,  Smad4 interacting transcriptional co activator,  Smad4-interact,  mRNA decapping enzyme 1A,  mRNA-decapping enzyme 1A
Swissprot
Calculated MW 63 kDa
Cellular Localization Cytoplasm>P-body. Nucleus. Co-localizes with NANOS3 in the processing bodies (By similarity). Predominantly cytoplasmic, in processing bodies (PB). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4.
Concentration 0.7 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Decapping is a key step in general and regulated mRNA decay.The protein encoded by this gene is a decapping enzyme.This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons.This protein also participates in the TGF-beta signaling pathway.
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Unconjugated

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