DCP1A Polyclonal Antibody (E-AB-14933)
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For research use only.
Verified Samples |
Verified Samples in WB: Hela Verified Samples in IHC: Human cervical cancer, Human colon cancer |
Dilution | WB 1:1000-1:5000, IHC 1:100-1:300 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human DCP1A |
Abbre | DCP1A |
Synonyms | DCP1 decapping enzyme homolog A, DCP1A, Dcp1a, Decapping enzyme hDcp1a, Decapping mRNA 1A, HSA275986, Nbla00360, Putative protein product of Nbla00360, Smad4 interacting transcriptional co activator, Smad4-interact, mRNA decapping enzyme 1A, mRNA-decapping enzyme 1A |
Swissprot | |
Calculated MW | 63 kDa |
Cellular Localization | Cytoplasm>P-body. Nucleus. Co-localizes with NANOS3 in the processing bodies (By similarity). Predominantly cytoplasmic, in processing bodies (PB). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4. |
Concentration | 0.7 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Decapping is a key step in general and regulated mRNA decay.The protein encoded by this gene is a decapping enzyme.This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons.This protein also participates in the TGF-beta signaling pathway. |
Other Clones
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Unconjugated
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