DDAH1 Polyclonal Antibody (E-AB-16196)
For research use only.
Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human brain |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human DDAH1 |
Abbre | DDAH1 |
Synonyms | DDAH, DDAH I, DDAH-1, DDAH1, DDAHI, Dimethylargininase 1, Dimethylargininase-1, Dimethylarginine dimethylaminohydrolase 1, N(G), N(G)-dimethylarginine dimethylaminohydrolase 1, NG NG dimethylarginine dimethylaminohydrolase |
Swissprot | |
Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome, Mitochondrion. |
Concentration | 0.2 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues. |
Other Clones
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Other Formats
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Unconjugated
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