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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human brain
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human DDAH1
Abbre DDAH1
Synonyms DDAH,  DDAH I,  DDAH-1,  DDAH1,  DDAHI,  Dimethylargininase 1,  Dimethylargininase-1,  Dimethylarginine dimethylaminohydrolase 1,  N(G),  N(G)-dimethylarginine dimethylaminohydrolase 1,  NG NG dimethylarginine dimethylaminohydrolase
Swissprot
Cellular Localization Cytosol, Extracellular region or secreted, extracellular exosome, Mitochondrion.
Concentration 0.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
Other Clones

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Unconjugated

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