DIO1 Polyclonal Antibody (E-AB-11137)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human cervical cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human DIDO1 |
| Abbre | DIDO1 |
| Synonyms | BYE 1, BYE1, C20orf158, DATF 1, DATF-1, DIDO 1, DIDO 2, DIDO 3, DIDO1, DIDO2, DIDO3, DIO 1, DIO-1, DIO1, DKFZp434P111, Death associated transcription factor 1, Death inducer obliterator 1, Death-associated transcription factor 1, Death-inducer obliterator 1, dJ885L7.8 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Translocates to the nucleus after pro-apoptotic stimuli. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms. |
Other Clones
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Other Formats
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Unconjugated
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