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For research use only.

Verified Samples Verified Samples in IHC: Human esophagus cancer, Human breast cancer
Dilution IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human LIG1
Abbre LIG1
Synonyms DNA ligase 1,  DNA ligase I,  DNLI1,  LIG 1,  Ligase I DNA ATP dependent,  MGC117397,  MGC130025,  Polydeoxyribonucleotide synthase [ATP] 1,  lig1
Swissprot
Cellular Localization Nucleus.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Other Clones

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Unconjugated

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