DNA-RNA Hybrid Monoclonal Antibody[S9.6] (E-AB-48028)

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All	Size	Price	Qty
	100μL	$ 260.00	- +
	25μL	$ 90.00	- +

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Verified Samples	Verified Samples in IF: HeLa Verified Samples in ChIP: HeLa
Dilution	IF 1:200, ChIP 1:50-500,
Isotype	IgG2a
Host	Mouse
Reactivity	All
Applications	IF, ChIP
Immunogen	ΦX174 bacteriophage-derived synthetic DNA/RNA
Abbre	DNA-RNA Hybrid
Synonyms	DNA-RNA hybrid, RNA/DNA hybrid
Concentration	1 mg/mL
Buffer	PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Purification Method	Protein A/G Purification
Clone No.	S9.6
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
background	The DNA-RNA hybrids are a natural occurrence within eukaryotic cells and their level are high at sites of high transcriptional activity. They are non-canonical nucleic acid structures with transcriptional regulatory functions. Their presence is reported to predispose a locus to chromosomal breakage. The S9.6 monoclonal antibody recognizes DNA-RNA hybrids (also known as R-loops) and does not bind to single or double stranded DNA. The antibody has high affinity for DNA-RNA hybrids but also binds RNA-RNA hybrids that are AU-rich. The specificity of the antibody appears to be determined by a combination of sequence and structural dependency since R-loop sequence affects binding affinity.

Cat.No.	Product Name	Sizes
E-AB-1011	Goat Anti-Mouse IgG(H+L)(Cyanine3 conjugated)	500μL , 120μL , 60μL
E-AB-1015	Goat Anti-Mouse IgG(H+L)(FITC conjugated)	500μL , 120μL , 60μL
E-AB-1059	Goat Anti-Mouse IgG(H+L)(Elab Fluor^® 594 conjugated)	500μL , 120μL , 60μL
E-AB-1076	Goat Anti-Mouse IgG(H+L)(Elab Fluor^® 647 conjugated)	500μL , 120μL , 60μL
E-IR-R322	Immunol Fluorescence Staining Kit (Anti-Mouse IgG-Cyanine3)	200Assays , 100Assays , 50Assays
E-IR-R324	Immunol Fluorescence Staining Kit (Anti-Mouse IgG-FITC)	200Assays , 100Assays , 50Assays
E-IR-R326	Immunol Fluorescence Staining Kit (Anti-Mouse IgG-Elab Fluor^® 488)	200Assays , 100Assays , 50Assays
E-IR-R328	Immunol Fluorescence Staining Kit (Anti-Mouse IgG-Elab Fluor^® 594)	200Assays , 100Assays , 50Assays

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Unconjugated