DNM2 Polyclonal Antibody (E-AB-13205)
For research use only.
| Verified Samples |
Verified Samples in WB: Hela, NIH/3T3, Raji Verified Samples in IHC: Human gastric cancer, Human thyroid cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human DNM2 |
| Abbre | DNM2 |
| Synonyms | CMT2M, CMTDI1, CMTDIB, DI CMTB, DYN II, DYN2, DYNII, Dnm2, Dynamin II, Dynamin-2, Dynamin2, DynaminII |
| Swissprot | |
| Calculated MW | 98 kDa |
| Cellular Localization | Cytoplasm. Cytoplasm>cytoskeleton. Cell junction>synapse>postsynaptic cell membrane>postsynaptic density. Cell junction>synapse. Microtubule-associated. Also found in the postsynaptic density of neuronal cells. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. |
Other Clones
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Unconjugated
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