DOK1 Polyclonal Antibody (E-AB-10290)
For research use only.
Verified Samples |
Verified Samples in WB: Human hepatocellsular carcinoma, Jurkat |
Dilution | WB 1:500-1:2000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human DOK1 |
Abbre | DOK1 |
Synonyms | DOK 1, DOK1, Docking protein 1, Docking protein 1 62kD, Downstream of tyrosine kinase 1, P62DOK, p62(dok), pp62 |
Swissprot | |
Calculated MW | 52 kDa |
Cellular Localization | Cytoplasm and Cytoplasm>perinuclear region. |
Concentration | 0.5 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. |
Other Clones
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Other Formats
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Unconjugated
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