DR5/TRAIL R2 Monoclonal Antibody (AN200049P)
For research use only.
| Verified Samples | Verified Samples in IF: HCT116 |
| Dilution | ICC/IF 1:20-1:100, |
| Isotype | IgG1 |
| Host | Mouse |
| Reactivity | Human |
| Applications | ICC/IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human DR5/TRAIL R2 Protein |
| Abbre | TNFRSF10B |
| Synonyms | UNQ, PRO, Death Receptor, TRAIL Receptor, TNF-Related Apoptosis-Inducing Ligand Receptor, TRICK, ZTNFR, TRAILR, TRAIL-R, KILLER/DR, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9, TNFRSF10B, Death Receptor 5, TNF-Related Apoptosis-Inducing Ligand Receptor 2, TRAIL Receptor 2, Tumor Necrosis Factor Receptor Superfamily Member 10B, UNQ160, PRO186, DR5, KILLER, TNFRSF10b |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Cell Biology, Signal Transduction, Cancer, Cardiovascular |
| Clone No. | A893 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins. |
Other Clones
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Unconjugated
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