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For research use only.

Verified Samples Verified Samples in WB: Human liver
Verified Samples in IHC: Human lung cancer, Human gastric cancer
Dilution WB 1:500-1:2000,  IHC 1:30-1:150
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human DRD4
Synonyms D(2C) dopamine receptor,  D(4) dopamine receptor,  D(4) dopamine receptor (D(2C) dopamine receptor).,  D4 dopamine receptor,  D4DR,  DRD 4,  DRD4,  Dopamine D4 receptor,  Drd4
Swissprot
Calculated MW 48 kDa
Cellular Localization Cell membrane.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
Other Clones

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Unconjugated

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