DRD4 Polyclonal Antibody (E-AB-12360)
For research use only.
Verified Samples |
Verified Samples in WB: Human liver Verified Samples in IHC: Human lung cancer, Human gastric cancer |
Dilution | WB 1:500-1:2000, IHC 1:30-1:150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human DRD4 |
Synonyms | D(2C) dopamine receptor, D(4) dopamine receptor, D(4) dopamine receptor (D(2C) dopamine receptor)., D4 dopamine receptor, D4DR, DRD 4, DRD4, Dopamine D4 receptor, Drd4 |
Swissprot | |
Calculated MW | 48 kDa |
Cellular Localization | Cell membrane. |
Concentration | 0.4 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. |
Other Clones
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Other Formats
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Unconjugated
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