DSCR1 Polyclonal Antibody (E-AB-16188)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse heart, Mouse brain Verified Samples in IHC: Human liver cancer, Human brain |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human RCAN1 |
| Abbre | DSCR1 |
| Synonyms | Adapt 78, Adapt78, CSP 1, CSP1, Calcipressin 1, Calcipressin-1, Calcium and oxidant inducible mRNA, DSC 1, DSC1, DSCR 1, DSCR1, Down syndrome candidate region 1, Down syndrome critical region gene 1, Down syndrome critical region protein 1, MCIP 1, MCIP1, Modulatory calc |
| Swissprot | |
| Calculated MW | 28 kDa |
| Cellular Localization | Nucleus, Other locations: cytoplasm. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development.This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses.Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.Three transcript variants encoding three different isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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