DUSP11 Polyclonal Antibody (E-AB-17232)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer |
| Dilution | IHC 1:30-150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Abbre | DUSP11 |
| Synonyms | DUS11, DUSP11, Dual specificity phosphatase 11, Dual specificity protein phosphatase 11, PIR1, Phosphatase that interacts with RNA/RNP complex 1, RNA, RNA/RNP complex 1 interacting, RNA/RNP complex interacting phosphatase, RNA/RNP complex-1-interacting phosphatase |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 1.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. |
Other Clones
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Other Formats
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Unconjugated
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