E-Cadherin Monoclonal Antibody (E-AB-70249)
For research use only.
| Verified Samples |
Verified Samples in IHC: Mouse liver, Rat colon, Rat pancreas |
| Dilution | IHC 1:200-1:800 |
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Mouse, Rat |
| Applications | IHC |
| Clonality | Monoclonal |
| Immunogen | Recombinant protein corresponding to MouseE-cadherin |
| Abbre | E-Cadherin |
| Synonyms | Arc 1, CADH1, CAM 120/80, CD 324, CD324, CD324 antigen, CDHE, Cadherin 1, Cadherin1, E-Cad/CTF3, E-cadherin, ECAD, Epithelial cadherin, LCAM, Liver cell adhesion molecule, UVO, Uvomorulin, cadherin 1 type 1 E-cadherin, cdh1, epithelial calcium dependant adhesion protein |
| Swissprot | |
| Concentration | 1.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Developmental Biology, Signal Transduction |
| Clone No. | EC125D |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. |
Other Clones
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Other Formats
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Unconjugated
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