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For research use only.

Verified Samples Verified Samples in IHC: Human esophagus cancer, Human tonsil
Dilution IHC 1:50-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human EARS2
Abbre EARS2
Synonyms mitochondrial ,  3230401I01Rik,  AL024049,  COXPD12,  EARS 2,  GluRS,  Glutamate--tRNA ligase,  Glutamyl tRNA synthetase 2 mitochondrial,  MSE1,  Probable glutamyl tRNA synthetase,  Probable glutamyl-tRNA synthetase,  RGD1307904,  SYEM,  ears2,  mKIAA1970,  mitochondrial
Swissprot
Cellular Localization Mitochondrion matrix.
Concentration 0.9 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Epigenetics and Nuclear Signaling,  Metabolism,  Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants.
Other Clones

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Unconjugated

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