ECE2 Polyclonal Antibody (E-AB-14051)
For research use only.
Verified Samples |
Verified Samples in IHC: Human colon cancer, Human gastric cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human ECE2 |
Synonyms | ECE 2, ECE-2, ECE2, Endothelin converting enzyme 2, Endothelin-converting enzyme 2 region, Hypothetical protein MGC2408, KIAA0604, MGC17664, MGC78487 |
Swissprot | |
Cellular Localization | Golgi apparatus membrane. Cytoplasmic granule membrane. |
Concentration | 0.1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cardiovascular, Neuroscience, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family. It converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity. |
Other Clones
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Other Formats
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Unconjugated
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