Elab Bright™ Violet 421 Anti-Mouse CD49b/pan-NK cells Antibody[DX5] (E-AB-F1116Q2)
![Elab Bright™ Violet 421 Anti-Mouse CD49b/pan-NK cells Antibody[DX5] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: Elab Bright™Violet 421
APC Biotin Elab Bright™Violet 421 Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Red 780 Elab Fluor®Violet 450 FITC PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 PerCP PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Rat IgM, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Isotype Control | Elab Bright™ Violet 421 Rat IgM, κ Isotype Control[R4-22] |
| Abbre | CD49b |
| Synonyms | CD49 antigen-like family member B, CD49b, Collagen receptor, GPIa, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 subunit alpha, pan-NK cells |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Adhesion, Cell Biology, Immunology, Innate Immunity |
| Clone No. | DX5 |
| Conjugation | Elab Bright™Violet 421 |
| Conjugation Information | Elab BrightTM Violet 421 is designed to be excited by the violet laser (405 nm) and detected using an optical filter centered near 421 nm (e.g., a 450/50 nm bandpass filter). |
| Spectrum |
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| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen. |
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