Elab Fluor^®488 Anti-Human Ki-67 Antibody[3B7] (AN00540L)

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Cell Markers

Size	Price	Qty
100Tests	$ 278.00	- +
20Tests	$ 113.00	- +
10Tests	$ 0.99	- +
100Tests×2	$ 500.00	- +

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Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Human
Applications	ICFCM
Clonality	Monoclonal
Abbre	Ki-67
Synonyms	Antigen Ki-67
Swissprot	P46013
Cellular Localization	Nucleus
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Clone No.	3B7
Conjugation	Elab Fluor^®488
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	Antigen Ki-67 is a nuclear protein expressed as two isoforms with molecular weights of 395 and 345 kD. Both isoforms contain one forkhead-associated domain and 16 concatenated "Ki-67 repeats," each containing the epitope recognized by the mAb Ki-67. The antigen Ki-67 interacts with Hklp2, hNIFK, and chromobox protein homolog 1, 3, and 5. Ki-67 is required for cell proliferation and its expression is restricted to the phases G1, S, G2, and M of the cell cycle. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. Ki-67 has also been used to study myocyte proliferation after myocardial infarction as well as lymphocyte proliferation during infection, and has been used in neurons of patients with different neuropathologies.

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