Elab Fluor® 488-conjugated Vinculin Monoclonal Antibody (AN00297L)
For research use only.
| Verified Samples |
Verified Samples in IF: Hela |
| Dilution | IF 1:100-1:200 |
| Isotype | IgG1 |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant human Vinculin protein expressed by E.coli |
| Abbre | Vinculin |
| Synonyms | Metavinculin (MV), VCL, Vinculin |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton. Cell junction>adherens junction. Cell membrane. Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II-dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Protein A/G Purification |
| Research Areas | Cardiovascular, Signal Transduction, Isotype/Loading Controls, Epigenetics and Nuclear Signaling |
| Clone No. | Da-4D4 |
| Conjugation | Elab Fluor®488 |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| Amax | 493nm |
| Emax | 519nm |
| background | Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa,1,066-amino-acid protein which is ubiquitously expressed. Its splice variant,metavinculin (124 kDa),is muscle-specific. |
Other Clones
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Other Formats
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Elab Fluor®488
Elab Fluor®594
HRP
Unconjugated
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