Elab Fluor® 700 Anti-Human CD195 Antibody[RoAb13] (E-AB-F1418M1)
![Elab Fluor<sup>®</sup> 700 Anti-Human CD195 Antibody[RoAb13] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: Elab Fluor®700
Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 PE Unconjugated Show More
| Isotype | Mouse IgG2a, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM |
| Clonality | Monoclonal |
| Isotype Control | Elab Fluor® 700 Mouse IgG2a, κ Isotype Control[C1.18.4] |
| Abbre | CD195 |
| Synonyms | CCR5 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clone No. | RoAb13 |
| Conjugation | Elab Fluor®700 |
| Conjugation Information | Elab Fluor® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter). |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CCR5 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer. |
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