For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human cervical cancer |
| Dilution | IHC 1:40-1:200 |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ENSA |
| Abbre | ENSA |
| Synonyms | ARPP 19e , Alpha endosulfine , Endosulfine alpha |
| Swissprot | |
| Cellular Localization | Cytoplasmic |
| Concentration | 1.2 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Other Clones
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Unconjugated
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