ERK 2 Polyclonal Antibody (E-AB-70241)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil, Human lymphoma, Mouse kidney, Rat spleen |
| Dilution | IHC 1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein corresponding to Mouse ERK2 |
| Abbre | ERK 2 |
| Synonyms | ERK, ERK 2, ERK-2, ERT1, Extracellular Signal Regulated Kinase 2, Extracellular signal-regulated kinase 2, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAPK 1, MAPK 2, MAPK2, MK01, Mapk1, Mitogen-activated protein kinase 1, Mitogen-activated protein kinase 2, P38 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Cytoskeleton, Membrane, Nucleus. |
| Concentration | 30 μg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the MAP kinase family.MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.The activation of this kinase requires its phosphorylation by upstream kinases.Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity.The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
Other Clones
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Other Formats
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Unconjugated
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