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For research use only.

Verified Samples Verified Samples in WB: 293T, Human brain malignant glioma, Mouse brain, Human hepatocellsular carcinoma
Verified Samples in IHC: Human thyroid cancer, Human brain
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human MAPK1/MAPK3
Abbre ERK1/2
Synonyms ERK1,  ERK1/2,  ERK2
Swissprot
Calculated MW 41/43 kDa
Cellular Localization Cytoskeleton, Cytosol, Endosome, early endosome, late endosome, Extracellular region or secreted, extracellular exosome, Golgi apparatus, Golgi apparatus, Mitochondrion, Nucleus, nuclear envelope, nucleoplasm, nucleus, Plasma Membrane, caveola, plasma membrane, Other locations: cytoplasm, focal adhesion, protein complex, pseudopodium.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Neuroscience,  Signal Transduction,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Other Clones

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Unconjugated

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