ERP44 Polyclonal Antibody (E-AB-17493)
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For research use only.
| Verified Samples |
Verified Samples in WB: Raji, A549, Hela, HepG2, 231, K562, A431 Verified Samples in IHC: Human liver cancer |
| Dilution | WB 1:500-2000, IHC 1:25-100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ERP44 |
| Abbre | ERP44 |
| Synonyms | ER protein 44, ERP44, ERp44, Endoplasmic reticulum resident protein 44, Endoplasmic reticulum resident protein 44 kDa, Endoplasmic reticulum resident protein ERp44, KIAA0573, PDIA10, Protein disulfide isomerase family A, Thioredoxin domain containing 4 (, member 10 |
| Swissprot | |
| Calculated MW | 47 kDa |
| Cellular Localization | Endoplasmic reticulum lumen. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell biology, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | ERP44 is a 406 amino acid protein that contains one thioredoxin domain, a motif that participates in various redox reactions throughout the cell. Localized to the lumen of the endoplasmic reticulum (ER), TXNDC4 functions to inhibit the activity of IP3R-I (inositol 1,4,5-triphosphate receptor,type 1) within calcium channels. In addition, TXNDC4 is thought to regulate oxidative protein folding within the ER and may be involved in retaining proteins. |
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