FAN1 Polyclonal Antibody (E-AB-17946)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human lung cancer, Human ovarian cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human FAN1 |
| Abbre | FAN1 |
| Synonyms | 6030441H18Rik, Coiled coil domain containing protein MTMR15, DKFZp451H236, DKFZp686K16147, FAN1, FANCD2 and FANCI associated nuclease 1, FANCD2/FANCI associated nuclease 1 , FANCD2/FANCI-associated nuclease 1, Fanconi associated nuclease 1, Fanconi-associated |
| Swissprot | |
| Cellular Localization | Nucleus. Localizes at sites of DNA damage following recruitment by monoubiquitinated FANCD2. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity.Mutations in this gene cause karyomegalic interstitial nephritis.Alternatively spliced transcript variants encoding distinct isoforms have been described. |
Other Clones
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Other Formats
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Unconjugated
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