FBXW7 Polyclonal Antibody (E-AB-11064)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human cervical cancer, Human thyroid cancer |
| Dilution | IHC 1:100-1:300 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human FBXW7 |
| Abbre | FBXW7 |
| Synonyms | AGO, Archipelago, Archipelago homolog, CDC4, DKFZp686F23254, Drosophila, Drosophila), E3 ubiquitin protein ligase, F box and WD 40 domain protein 7, F box and WD 40 domain protein 7 (archipelago homolog, F box and WD repeat domain containing, F box and WD repeat domain containing 7, F box protein FBW7, F box protein FBX30, F box protein SEL 10, F box protein SEL10, F-box and WD repeat domain containing 7, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, F-box/WD repeat-containing protein 7, FBW6, FBW7, FBX30, FBXO30, FBXW6, FBXW7, FLJ16457, hAgo, hCdc4, homolog of, Homolog of C elegans sel 10, Homolog of C.elegans sel10, S.cerevisiae, SEL 10, SEL-10, SEL10抗体 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Nucleus, Nucleus>nucleolus and Nucleus>nucleoplasm. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. |
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