FGFR1OP Polyclonal Antibody (E-AB-15032)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse heart, NIH/3T3, Mouse liver Verified Samples in IHC: Human brain, Human cervical cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human FGFR1OP |
| Abbre | FGFR1OP |
| Synonyms | FOP |
| Swissprot | |
| Calculated MW | 43 kDa |
| Cellular Localization | Cytoskeleton, centriole, centrosome, Cytosol, Nucleus, Other locations: cell projection, perinuclear region of cytoplasm. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. |
Other Clones
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Other Formats
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Unconjugated
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