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For research use only.

Verified Samples Verified Samples in IHC: Human colorectal cancer, Human cervical cancer
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human FGR
Abbre FGR
Synonyms FGR,  FLJ43153,  Fgr,  Gardner Rasheed feline sarcoma viral (v fgr),  Gardner Rasheed feline sarcoma viral (v fgr) oncogene homolog,  Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog,  MGC75096,  c fgr,  c fgr protooncogene,  c src 2 proto oncogene,  c src2,  p55
Swissprot
Cellular Localization Cell membrane. Cell membrane. Cell projection>ruffle membrane. Cytoplasm>cytosol. Cytoplasm>cytoskeleton. Mitochondrion inner membrane. Mitochondrion intermembrane space. Detected in mitochondrial intermembrane space and at inner membranes (By similarity). Colocalizes with actin fibers at membrane ruffles. Detected at plasma membrane lipid rafts.
Concentration 2.04 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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Unconjugated

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