FH Polyclonal Antibody (E-AB-15051)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse liver, Mouse brain, Mouse heart, RAW264.7 Verified Samples in IHC: Human liver cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human FH |
| Abbre | FH |
| Synonyms | FH, FUMH, Fumarase, Fumarate hydratase, Fumarate hydratase mitochondrial, HLRCC, LRCC, MCL, MCUL 1, MCUL1, MS709, Multiple hereditary cutaneous leiomyomata, mitochondrial |
| Swissprot | |
| Calculated MW | 55 kDa |
| Cellular Localization | Cytoplasm and Mitochondrion. |
| Concentration | 0.7 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. |
Other Clones
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Other Formats
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Unconjugated
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