FITC Anti-Human CD117/c-Kit Antibody[104D2] (E-AB-F1150C)

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Size	Price	Qty
100Tests	$ 220.00	- +
20Tests	$ 75.00	- +
100Tests×2	$ 330.00	- +

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Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Abbre	CD117
Synonyms	CD117, Kit, Mast/stem cell growth factor receptor Kit, Proto-oncogene c-Kit, SCFR, Tyrosine-protein kinase Kit, c-Kit
Swissprot	P10721
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology, Stem Cells
Clone No.	104D2
Conjugation	FITC
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.