FITC Anti-Human CD127/IL-7RA Antibody[A019D5] (E-AB-F1152C)

Name: FITC Anti-Human CD127/IL-7RA Antibody[A019D5]
Brand: Elabscience
SKU: E-AB-F1152C
Price: 90.0 USD
Availability: InStock

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Cell Markers

FITC Anti-Human CD127/IL-7RA Antibody[A019D5] - 1

Size	Price	Qty
100Tests	$ 220.00	- +
20Tests	$ 90.00	- +
100Tests×2	$ 330.00	- +

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Conjugation: FITC

APC Biotin Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Red 780 Elab Fluor®Violet 450 FITC PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 PerCP/Cyanine 5.5 Unconjugated Show More Show Less

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Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Isotype Control	FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Abbre	CD127
Synonyms	CD127, CDw127, IL-7RA, IL-7Rα, Interleukin-7 receptor subunit alpha
Swissprot	P16871
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology
Clone No.	A019D5
Conjugation	FITC
Conjugation Information	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.