FITC Anti-Human CD14 Antibody[18D11] (AN00361C)
![FITC Anti-Human CD14 Antibody[18D11] - 1](http://file.elabscience.com/assets/images/loading.png)
| Alternate Names | Monocyte differentiation antigen CD14 |
| Clone | |
| Background | CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup. |
| Abbre | CD14 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1, κ |
| Isotype Control | FITC Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Cellular Localization |
Membrane;Secreted
|
| Form | Liquid |
| Concentration |
5 μL/Test
|
| Conjugation | FITC |
| Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 24 months |
| Shipping | Ice bag |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| AN00420C | FITC Anti-Human CD14 Antibody[UCHM-1] | UCHM-1 |
| AN00868C | FITC Anti-Human CD14 Antibody[63D3] | 63D3 |
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