FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] (E-AB-F1229C)
For research use only.
Background | Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion. |
Alternate Names | PD1, PDCD1, Protein PD-1, hPD-1 |
Swissprot | |
Clone No | |
Host | Mouse |
Reactivity | Human |
Isotype | Mouse IgG1, κ |
Isotype Control | |
Application |
FCM
|
Cellular Localization |
Membrane
|
Form | Liquid |
Conjugation | FITC |
Conjugation information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration date | 12 months |
Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®647
Elab Fluor®Red 780
FITC
PE
PE/Cyanine 5.5
PE/Cyanine 7
PerCP/Cyanine 5.5
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