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All Size Price Qty
100Tests $ 174.00
20Tests $ 66.00
100Tests×2 $ 264.00
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For research use only.

Background Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Alternate Names PD1,  PDCD1,  Protein PD-1,  hPD-1
Swissprot
Clone No
Host Mouse
Reactivity Human
Isotype Mouse IgG1, κ
Isotype Control
Application
FCM
Cellular Localization
Membrane
Form Liquid
Conjugation
FITC
Conjugation information FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date 12 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

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Other Formats

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APC

Biotin

Elab Fluor®647

Elab Fluor®Red 780

FITC

PE

PE/Cyanine 5.5

PE/Cyanine 7

PerCP/Cyanine 5.5

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