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100Tests $ 75.00
50Tests $ 45.00
100Tests×2 $ 115.00
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For research use only.

Alternate Names Programmed Death-1,  PD-1
Clone No
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Background CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
Abbre CD279
Swissprot
Host Rat
Reactivity Mouse
Clonality Monoclonal
Isotype Rat IgG2a, κ
Isotype Control E-AB-F09832C
Applications
FCM
Research Areas Cancer Biomarkers;Immunology;Inhibitory Molecules
Cellular Localization
Membrane
Form Liquid
Concentration
5 μL/Test
Conjugation FITC
Conjugation Information FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date 12 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

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Other Formats

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APC

Biotin

Elab Fluor®647

Elab Fluor®700

Elab Fluor®Red 780

FITC

None (AF/LE)

PE

PE/Cyanine 5.5

PE/Cyanine 7

PerCP/Cyanine 5.5

Unconjugated

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