FoxO3a Polyclonal Antibody (E-AB-62081)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Rat brain, Human liver damage Verified Samples in IF: C6, NIH/3T3, U-2OS |
| Dilution | IHC 1:50-1:200, IF 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of mouse FoxO3a (NP_062714.1). |
| Abbre | FoxO3a |
| Synonyms | AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3, FOXO3A |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. |
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