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For research use only.

Verified Samples Verified Samples in WB: Human brain
Verified Samples in IHC: Human breast cancer, Human esophagus cancer
Dilution WB 1:500-1:2000,  IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human FTO
Abbre FTO
Synonyms ALKBH9,  AW743446,  AlkB homolog 9,  Alpha-ketoglutarate-dependent dioxygenase FTO,  FATSO,  FTO,  Fat mass and obesity-associated protein,  Fto,  GDFD,  HOMOLOG OF,  KIAA1752,  MOUSE,  Protein fatso,  mKIAA1752
Swissprot
Calculated MW 58 kDa
Cellular Localization Nucleus.
Concentration 0.7 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Other Clones

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Unconjugated

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