FTO Polyclonal Antibody (E-AB-11248)
For research use only.
Verified Samples |
Verified Samples in WB: Human brain Verified Samples in IHC: Human breast cancer, Human esophagus cancer |
Dilution | WB 1:500-1:2000, IHC 1:100-1:300 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human FTO |
Abbre | FTO |
Synonyms | ALKBH9, AW743446, AlkB homolog 9, Alpha-ketoglutarate-dependent dioxygenase FTO, FATSO, FTO, Fat mass and obesity-associated protein, Fto, GDFD, HOMOLOG OF, KIAA1752, MOUSE, Protein fatso, mKIAA1752 |
Swissprot | |
Calculated MW | 58 kDa |
Cellular Localization | Nucleus. |
Concentration | 0.7 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. |
Other Clones
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Other Formats
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Unconjugated
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