GAD2 Polyclonal Antibody (E-AB-15661)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human brain |
| Dilution | IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GAD2 |
| Abbre | GAD2 |
| Synonyms | 65 kDa glutamic acid decarboxylase, DCE 2, DCE2, GAD 2, GAD 65, GAD-2, GAD-65, Gad2, Glutamate Decarboxylase 2 (pancreatic islets and brain 65kDa), Glutamate Decarboxylase 65, Glutamate decarboxyla, Glutamate decarboxylase 2, Glutamate decarboxylase 2 (pancreas) |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytosol. Cytoplasmic vesicle. Cell junction>synapse>presynaptic cell membrane. Golgi apparatus membrane. Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
Other Clones
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Other Formats
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Unconjugated
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