GADD45B Polyclonal Antibody (E-AB-11252)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human brain |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human GADD45B |
| Abbre | GADD45B |
| Synonyms | GA45B, GADD45 Beta, GADD45BETA, Gadd45b, Growth arres, Growth arrest and DNA damage inducible 45 beta, Growth arrest and DNA damage inducible beta, Growth arrest and DNA damage-inducible gene GADD45, Growth arrest and DNA damage-inducible protein GADD45 beta, beta |
| Swissprot | |
| Cellular Localization | Nucleus, Other locations: cytoplasm. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. |
Other Clones
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Other Formats
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Unconjugated
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