Galectin-3 Polyclonal Antibody (AN000300P)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer Verified Samples in IF: NIH-3T3 Verified Samples in ELISA: Recombinant Human Galectin-3 protein, Human serum, Human plasma |
| Dilution | IHC 1:650-1:1250, IF 1:50-1:200, ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA Capture/Detector |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human Galectin-3 protein expressed by E.coli |
| Abbre | Galectin-3 |
| Synonyms | GAL3, GaL-3, GaLectin-3, 35 kDa Lectin, Carbohydrate-binding protein 35 (CBP 35), GaLactose-specific Lectin 3, GaLactoside-binding protein (GALBP), IgE-binding protein, LGALS3, MAC2 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Neuroscience, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | Galactose-specific lectin which binds IgE. May mediate with the alpha-3,beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1,required for terminal differentiation of columnar epithelial cells during early embryogenesis.In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion,chemoattraction of monocytes macrophages,opsonization of apoptotic neutrophils,and activation of mast cells. Together with TRIM16,coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16l1 and BECN1 in response to damaged endomembranes. |
Other Clones
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Other Formats
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Unconjugated
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