GFRA3 Polyclonal Antibody (E-AB-15686)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human esophagus cancer |
| Dilution | IHC 1:50-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GFRA3 |
| Abbre | GFRA3 |
| Synonyms | GDNF family receptor alpha 3, GDNF family receptor alpha-3, GDNF receptor alpha-3, GDNFR-alpha-3, GDNFR3, GFR-alpha-3, GFRA3, GPI linked receptor, Glial cell line derived neurotrophic factor receptor alpha 3, OTTHUMP00000159486, OTTHUMP00000224020 |
| Swissprot | |
| Cellular Localization | Cell membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression. |
Other Clones
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Other Formats
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Unconjugated
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