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For research use only.

Verified Samples Verified Samples in IHC: Human breast cancer, Human liver cancer
Dilution IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human GGCX
Abbre GGCX
Synonyms FLJ26629,  GC,  GGCX,  Gamma glutamyl carboxylase,  Gamma-glutamyl carboxylase,  Peptidyl glutamate 4 carboxylase,  Peptidyl-glutamate 4-carboxylase,  VKCFD,  Vitamin K dependent gamma carboxylase,  Vitamin K gamma glutamyl carboxylase,  Vitamin K-dependent gamma-carboxylase
Swissprot
Cellular Localization Endoplasmic reticulum membrane.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cardiovascular
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
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Unconjugated

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